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Inside good pilot data, Sullivan and you may acquaintances (2013) analyzed using endoscopic aspiration medication for the treatment of obesity

Inside good pilot data, Sullivan and you may acquaintances (2013) analyzed using endoscopic aspiration medication for the treatment of obesity

AspireAssist Ambition Cures

This method entails endoscopic placement of a gastrostomy tube (A-Tube) and the AspireAssist siphon assembly (Aspire Bariatrics, King of Prussia, PA) to aspirate gastric contents 20 minutes after meal consumption. These researchers performed a study of 18 obese subjects who were randomly assigned (2:1) to groups that underwent aspiration therapy for 1 year plus lifestyle therapy (n = 11; mean BMI, 42.6 ± 1.4 kg/m(2)) or lifestyle therapy only (n = 7; mean BMI, 43.4 ± 2.0 kg/m(2)). Lifestyle intervention comprised a 15-session diet and behavioral education program; 10 of the 11 subjects who underwent aspiration therapy and 4 of the 7 subjects who underwent lifestyle therapy completed the 1st year of the study. After 1 year, subjects in the aspiration therapy group lost 18.6 % ± 2.3 % of their body weight (49.0 % ± 7.7 % of EWL) and those in the lifestyle therapy group lost 5.9 % ± 5.0 % (14.9 % ± 12.2 % of EWL) (p < 0.04); 7 of the 10 subjects in the aspiration therapy group completed an additional year of therapy and maintained a 20.1 % ± 3.5 % body weight loss (54.6 % ± 12.0 % of EWL). There were no AEs of aspiration therapy on eating behavior and no evidence of compensation for aspirated calories with increased food intake. No episodes of binge eating in the aspiration therapy group or serious AEs were reported. The authors concluded that aspiration therapy appeared to be a safe and effective long-term weight loss therapy for obesity. These preliminary findings from a pilot study need to be validated by well-designed studies.

Forssell and you will Noren (2015) analyzed the potency of a book unit, this new AspireAssist aspiration therapy program, for the treatment of carrying excess fat. Immediately after a month taking an extremely-low-fat eating plan, twenty-five overweight people (Body mass index 39.8 ± 0.nine kilogram/m(2)) encountered the AspireAssist gastrostomy tubing place throughout the an effective gastroscopy. A minimal-profile device is installed two weeks afterwards and ambition out of gastric information are did whenever 20 minutes just after items 3 times for every single time. Cognitive behavioral medication was also started. From the week 6, mean weight destroyed was 16.5 ± seven.8 kilogram about 22 subjects just who completed twenty six days out of cures (p = 0.001). The fresh suggest payment EWL was forty.8 ± 19.8 % (p = 0.001); 2 sufferers had been hospitalized getting challenge: step 1 topic for aches once gastrostomy tubing positioning, which was addressed with analgesics, plus one due to an aseptic intra-intestinal liquid range 24 hours once gastrostomy tube position. No clinically tall changes in solution potassium or any other electrolytes occurred. The fresh new authors determined that in this data, large slimming down was attained that have partners complications with the AspireAssist system, indicating its potential once the an attractive healing unit getting fat customers.

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In a prospective observational study, Noren and Forssell (2016) evaluated the safety and effectiveness of the novel AspireAssist Aspiration Therapy System for treatment of obesity, and its effect on patient’s quality of life. A total of 25 obese subjects, mean age of 48 years (range of 33 to 65) were included in this study. A custom gastrostomy tube (A-tube) was percutaneously inserted during a gastroscopy performed under conscious sedation. Drainage and irrigation of the stomach were performed 3 times daily, 20 mins after each meal, for 1 to 2 years. Treatment included a cognitive behavioral weight loss program. Mean BMI at inclusion was 39.8 kg/m2 (range of 35 to 49). After https://datingranking.net/cs/dominicancupid-recenze/ 1 year mean (SD) BMI was 32.1 kg/m2 (5.4), p < 0.01, and EWL was 54.4 % (28.8), p < 0.01. Quality of life, as measured with EQ-5D, improved from 0.73 (0.27) to 0.88 (0.13), p < 0.01. After 2 years BMI was 31.0 kg/m2 (5.1), p < 0.01, and EWL was 61.5 % (28.5), p < 0.01. There were no serious AEs or electrolyte disorderspliance was 80 % after 1 year and 60 % after 2 years. The authors concluded that aspiration therapy is a safe and efficient treatment for obesity, and weight reduction improves quality of life. Excess weight was approximately halved in a year, with weight stability if treatment was continued; and long-term results remain to be investigated.






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